![]() ![]() If you like the tried and true, however, stick to retinol and tretinoin for now and re-examine the question in a couple of years when (hopefully) more research will be available. Pretty encouraging, though we are very much waiting for a study to confirm all this on real human beings.īottom line: We are really happy to see some innovation happening with retinoids, and we think Hydroxypinacolone Retinoate is a super promising rising star, but it’s not fully proven yet. If you are someone who likes to experiment and try out the newest things, grab your running shoes and try some HPR containing serum now (see product list below :)). however, HPR did not achieve gene transcription levels of ATRA (tretinoin)." But, a much higher dose might be tolerated from HPR and the highest dose of HPR out-performed tretinoin. The results are pretty encouraging showing that " HPR had greater levels of gene transcription than retinol and RP (RP) at the same concentrations. Regarding anti-aging, there is a pretty recent, Estee Lauder sponsored study that compared the in-vitro (not on real human beings but on skin models) collagen-boosting effectiveness of Hydroxypinacolone Retinoate, tretinoin, good old retinol and retinyl palmitate (RP). The Ordinary Retinol In Squalane có thit k ti gin, lp v màu ti giúp bo qun sn phm bên trong khi ánh nng mt tri d dàng hn. Both studies found the formulas effective but they contained other things too, so it's hard to judge how well HPR did. We found two Italian studies both examining the efficacy of HPR combined with other things (retinol in both cases, and papain in one of them) for the treatment of acne. But, before you do, you have to know that the info we have about HPR at the moment is mainly from the manufacturer, whose tests may or may not be accurate or properly designed (such as controlled, double-blind and conducted on an appropriate number of people).Īs HPR is pretty new there isn't that much independent research we could find yet. /rebates/2fp2fretinol-05-in-squalane-pimprod2007127&. These results sound sooo promising that we don't blame you if you wanna run out right now and get an HPR formula to slather on your face. Also, there was a "dramatic reduction of lines and wrinkles" after applying 0.2% HPR around the eyes twice a day for 14 days. According to the manufacturer's tests, 24 hours of an occlusive patch with 0.5% HPR resulted in significantly lower irritation than 0.5% retinol. The big promise of HPR is that it's similarly active as retinoic acid (no conversion needed, remember) but without the irritation. It binds directly to the retinoid receptors of the skin cells to work its skincare magic. Other forms of retinoids have to be converted by our metabolic machinery to do something. The Ordinary Granactive Retinoid 2 Emulsion, previously known as Advanced Retinoid 2, is one of the most-popular Retinoid-based products from the skincare. O entrega más rápida el Jueves, 23 de Marzo. Entrega GRATIS el Domingo, 26 de Marzo si compras 25 en artículos enviados por Amazon. ![]() US1980 (US19.80 / Fl Oz) Recibe entrega rápida y GRATIS con Amazon Prime Devoluciones GRATIS. If you've already read our description about retinol or retinyl palmitate, you know that the active ingredient our skin cells can interpret is retinoic acid. : The Ordinary, Retinoide avanzado al 2 (1.01 fl oz) : Salud y Hogar. Squalane, C12-15 Alkyl Benzoate, Bisabolol, Dimethyl Isosorbide, Hydroxypinacolone Retinoate, Solanum Lycopersicum (Tomato) Fruit Extract, Simmondsia Chinensis (Jojoba) Seed Oil.It's a so-called retinoic acid ester, meaning that it's directly related to retinoic acid. If irritation occurs, cease use and consult a physician. Do not use with other retinoid treatments. You need to apply a few drops of this product on your cleansed and completely dried face, wait for about 10 minutes for the product to sink in and then go ahead with heavier creams. Granactive Retinoid, an active technology from Grant Industries, is a solubilized system of Hydroxypinacolone Retinoate, a highly-advanced form of retinoid which is, in fact, a non-prescription ester of all-trans direct retinoic acid that offers a multi-fold better effect against signs of aging than retinol, retinyl palmitate and nearly all other forms of non-prescription retinoid.Īpply a small amount to face in the PM as part of your skincare regimen, after water-based serums but before heavier treatments. Retinol is also unstable in water, hence The Ordinary Retinol 0.2 in Squalane is a water-free formula, and feels like a light oil on the skin. This water-free solution contains a 2% concentration of an advanced retinoid active complex called Granactive Retinoid that has been shown to offer better results against multiple signs of aging than retinol without any of the irritation and drawbacks common with retinol. ![]()
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